Welcome to our laboratory website!
Our research group investigates the effect of estrogen on neurons in the brain. Estrogen secreted from the ovary, as a classical feedback molecule, alters the function of several neuronal phenotypes. Although estrogen is primarily thought to alter the neuronal activity via modulating gene expression directly, it also exerts “non-classical” effects on neurons by altering signal transduction pathways. In our laboratory, we systematically characterize the mechanism and role of estrogen-induced “non-classical” effect on signalling molecules in neurons using immunohistochemistry, calcium imaging, single cell electrophysiology, single molecule detection and transgenic technology.
If you have any questions or queries about our research please do not hesitate to contact us.
Wishing you an exciting visit,
With best regards,
István Ábrahám MD, PhD, DSc